6-deoxy-D-glucose crystalline - Names and Identifiers
6-deoxy-D-glucose crystalline - Physico-chemical Properties
Molecular Formula | C6H12O5
|
Molar Mass | 164.16 |
Density | 1.1738 (rough estimate) |
Melting Point | 146° |
Boling Point | 211.61°C (rough estimate) |
Specific Rotation(α) | D20 +73° (5 min) +30° (3 hr, final) (c = 8.3 in water) |
Solubility | H2O: 10 mg/mL, clear, colorless |
Merck | 13,8169 |
pKa | 12.50±0.20(Predicted) |
Storage Condition | −20°C |
Refractive Index | 1.4230 (estimate) |
6-deoxy-D-glucose crystalline - Risk and Safety
Safety Description | 24/25 - Avoid contact with skin and eyes.
|
WGK Germany | 3 |
FLUKA BRAND F CODES | 3-10 |
HS Code | 29400090 |
6-deoxy-D-glucose crystalline - Introduction
6-Deoxy-d-glucose is a derivative of glucose that lacks a hydroxyl group on the sixth carbon in its molecular structure. The following is a detailed description of its nature, use, preparation and safety information:
1. Nature:
-Appearance: colorless crystalline powder or crystalline solid
-Solubility: Soluble in water and a few organic solvents (such as methanol and ethanol)
-Melting point: About 140-142 degrees Celsius
-Chemical properties: Compared with glucose, 6-deoxy-d-glucose shows different properties in certain chemical reactions, such as the effect on enzymes, glycolysis and sugar metabolism.
2. Use:
-Biochemical Research: 6-Deoxy-d-glucose is commonly used in biochemistry and cell biology research, as a regulator of sugar metabolism, an inhibitor of sugar transport, or used as a labeling substance for cell tracing and glucose flux determination.
-Medical applications: Due to its glucose-like structure, 6-deoxy-d-glucose is used in the medical field to study cancer diagnosis and treatment, positron emission computed tomography (PET) examination is performed as by injection of Radioisotope labeled 6-deoxy-d-glucose.
3. Preparation method:
6-Deoxy-d-glucose can be prepared from glucose or other related raw materials through a series of chemical synthesis steps. The specific synthesis method depends on the needs of laboratory or industrial production.
4. Safety Information:
-6-Deoxy-d-glucose is a relatively safe compound, but normal operating procedures for chemicals should be followed to avoid direct contact with skin and eyes.
-It should be stored in a dry, well-ventilated place, away from heat sources and flames, and away from oxidants.
-It is necessary to properly dispose of the waste compounds and dispose of them according to local regulations.
Last Update:2024-04-09 21:04:16